We are a small research group based in the Division of Genome Information Sciences, Department of Pediatrics at the University of California, San Diego. We have strong ties with the Department of Computer Science and Engineering and the Bioinformatics and Systems Biology program.

Research in the group is focused on developing computational methods for variant calling in human genomes (particularly challenging types of variants) using high-throughput DNA sequencing technologies and identifying rare variants in human disease (young-onset diabetes) using a combination of bioinformatics, statistical modeling and large-scale data analysis.