Research in the lab is centered on human genetic variation and involves analysis of data from high-throughput sequencing technologies. We develop computational and statistical methods for challenging problems in human genetics/genomics and apply these methods to understand human disease. Current projects in the lab focus on several related topics:
1. development of computational methods for the detection of DNA sequence variation using high-throughput sequencing technologies (focus on challenging variant types such as short indels and haplotypes). This frequently involves technology development on the lab side as well.